Savant Journal of Medicine and Medical Sciences (SJMMS)
September 2016 Vol. 2(7), pp. 159-168

Copyright © 2016 Savant Journals


Original Research Paper

The Influence of Patient Demographics, Stage of Disease, and History of Corticosteroid Injections on the Effectiveness of Platelet-Rich Plasma in the Treatment of Knee Osteoarthritis

YASEMIN OZKAN1, SİNEM GÖKÇE2, GÖKÇEN GÖKÇE3

1Assistant Professor, M.D., Dumlupinar University, School of Medicine, Department of Physical Therapy and Rehabilitation, Kutahya, Turkey. 2Assistant Professor, M.D., Adana Research and Education Hospital, Department of Ear, Nose and Throat. Adana, Turkey. 3Assistant Professor, M.D., Dumlupinar University, School of Medicine, Department of Histology and Embryology, Kutahya, Turkey.

*Corresponding Author E-mail: ftrjo@hotmail.com

Accepted 22nd August, 2016


Abstract

Objective: The purpose of our study was to determine the effect of PRP administrations, on pain, Cincinnati Knee Rating System and the Lysholm Knee Score in patients with osteoarthritis of the knee. In addition, we wanted to explore the relation of PRP treatment with the stage of osteoarthritis, BMI, age, gender, and intraarticular steroid administration within the last 6 months. Materials and Methods: This study was done on 371 osteoarthritic knees of 295 patients, who were 40 to 65 years of age. The patients were interviewed for age, gender, BMI, and history of intraarticular steroid injections within the last 6 months. The patients were evaluated using VAS, the Cincinnati Knee Rating System, and the Lysholm Knee Score at 1, 3, and 6 months following two intraarticular PRP injections with an interval of 4 weeks. The relation of these results with demographic data was investigated. Results: This study shows that PRP treatment is a safe and effective method that can be used in the treatment of knee osteoarthritis. Reduction of pain and clinical improvement were observed in all patients after the treatment, and the stage of knee osteoarthritis, BMI, age, and intraarticular steroid injections within 6 months were directly related to the effectiveness of PRP treatment. Conclusion: The stage of knee osteoarthritis, BMI, age, and intraarticular steroid injections within 6 months are important demographic data that require evaluation in patients for whom PRP treatment is planned. These parameters should be taken into account when selecting the patients for PRP injections.

Keywords: Osteoarthritis,knee, platelet-rich plasma, Physician's Practice Patterns